Name   |
Location   |
Market price   |
Quest |
Members Only |
| Sealed small rune pouch (orange) | Player Made (See Notes). | --- | No | Yes |
| Sealed small rune pouch (pink) | Player Made (See Notes). | --- | No | Yes |
| Sealed small rune pouch (purple) | Player Made (See Notes). | --- | No | Yes |
| Sealed small rune pouch (red) | Player Made (See Notes). | --- | No | Yes |
| Sealed small rune pouch (yellow) | Player Made (See Notes). | --- | No | Yes |
| Searing ashes | Monster drop. | 58.4k gp | No | Yes |
| Searing flame | Picked up in Char's Training Cave, west of the Tree Gnome Stronghold. | --- | No | Yes |
| Searing overload potion (1) | Player made (See Notes). | --- | No | Yes |
| Searing overload potion (2) | Player made (See Notes). | --- | No | Yes |
| Searing overload potion (3) | Player made (See Notes). | --- | No | Yes |
| Searing overload potion (4) | Player made (See Notes). | --- | No | Yes |
| Searing overload potion (5) | Player made (See Notes). | --- | No | Yes |
| Searing overload potion (6) | Player made (See Notes). | --- | No | Yes |
| Seaside rock | This item was a reward from the discontinued Squeal of Fortune. | --- | No | No |
| Seasinger kiba | Player made (See Notes Section). | --- | No | Yes |
| Seasinger makigai | Player made (See Notes Section). | --- | No | Yes |
| Seasinger's hood | Player made (See Notes Section). | 4.5m gp | No | Yes |
| Seasinger's robe bottom | Player made (See Notes Section). | 8.4m gp | No | Yes |
| Seasinger's robe top | Player made (See Notes Section). | 10.2m gp | No | Yes |
| Seaweed (Raktuber) | Located on a hat-rack, on the penguin submarine. | --- | Yes | Yes |
| Secateurs | Dropped by Farmers, bought from Farming shops. | 1,236 gp | No | Yes |
| Second dragonkin journal | Obtained from killing the Queen Black Dragon and claiming the reward from the chest. | --- | No | Yes |
| Second stone fragment | The second stone fragment is found South East of the Ancient statue on Mazcab. | --- | No | Yes |
| Second wind scroll (tier 1) | Player made (See Notes Section). | 0 gp | No | Yes |
| Second wind scroll (tier 10) | Player made (See Notes Section). | 0 gp | No | Yes |
| Second wind scroll (tier 2) | Player made (See Notes Section). | 0 gp | No | Yes |
| Second wind scroll (tier 3) | Player made (See Notes Section). | 0 gp | No | Yes |
| Second wind scroll (tier 4) | Player made (See Notes Section). | 0 gp | No | Yes |
| Second wind scroll (tier 5) | Player made (See Notes Section). | 0 gp | No | Yes |
| Second wind scroll (tier 6) | Player made (See Notes Section). | 0 gp | No | Yes |
| Second wind scroll (tier 7) | Player made (See Notes Section). | 0 gp | No | Yes |
| Second wind scroll (tier 8) | Player made (See Notes Section). | 0 gp | No | Yes |
| Second wind scroll (tier 9) | Player made (See Notes Section). | 0 gp | No | Yes |
| Second-Age range coif | Possible reward from a Reward casket (master). | 89.7m gp | No | Yes |
| Second-Age range legs | Possible reward from a Reward casket (master). | 270.9m gp | No | Yes |
| Second-Age range top | Possible reward from a Reward casket (master). | 254.5m gp | No | Yes |
| Second-Age robe bottom | Possible reward from a Reward casket (master). | 719.4m gp | No | Yes |
| Second-Age robe top | Possible reward from a Reward casket (master). | 702.4m gp | No | Yes |
| Second-Age sword | Possible reward from a Reward casket (master). | 224.0m gp | No | Yes |
| Security Block | During The Void Stares Back, you obtain this by killing pests in one of the puzzle rooms. | --- | Yes | Yes |
| Security book | Bought from a General store or found in the bookcase of your Player-Owned House. | 767 gp | No | No |
| Security Casket (CS Week) | Can be received when a Clue Scroll(CS Week) has been fully solved, if your account is secure enough. | --- | No | No |
| Sedimentary geode | Occasionally obtained while Mining any of the following rocks:
Copper,
Tin,
Iron,
Coal,
Mithril,
Adamantite,
Luminite, and
Runite. | --- | No | No |
| Seed dibber | Dropped by farmers; Purchased at farming shops. | 1,054 gp | No | No |
| Seeker gland | In the quest dungeon, it is obtained by inspecting the dead Seeker of Truth. | --- | Yes | Yes |
| Seeker's charm | Monster Drop. | 128.5k gp | No | Yes |
| Seeker's charm (Dungeoneering) | Monster Drop. | 0 gp | No | Yes |
| Seeping elm branches | The Seeping elm branches (Tier 2) is an item that can only be obtained while Dungeoneering. They may be purchased from the Smuggler, received as a monster drop, or cut from a Seeping elm tree. | 0 gp | No | Yes |
| Seeping elm shortbow | Monster drop; player made (See Notes Section). | 0 gp | No | No |
| Seeping elm shortbow (u) | Player made (See Notes Section). | 0 gp | No | Yes |
| Seeping elm trap | Player made (See Notes Section). | 0 gp | No | Yes |
| Seer's headband 1 | Obtained from any Seer within Seers' Village. | --- | No | Yes |
| Seer's headband 2 | Obtained from Stankers (must have the previous tier headband). | --- | No | Yes |
| Seer's headband 3 | Obtained from Sir Kay (must have the previous tier headband). | --- | No | Yes |
| Seer's headband 4 | Obtained from Sir Kay (must have the previous tier headband). | --- | No | Yes |
| Seercull | Monster drop. | 69.6k gp | No | Yes |
| Seers' key | Player made (See Notes Section). | --- | Yes | Yes |
| Seers' ring | Monster drop. | 12.8m gp | No | Yes |
| Seers' ring (i) | Player made (See Notes Section). | --- | No | Yes |
| Seers' ring shard | Monster drop. | 1,778 gp | No | Yes |
| Seiryu's claw | Dropped by Arhat in Aminishi's Spirit Realm. | --- | No | Yes |
| Seiryu's fang | Purchased from Boni. | --- | No | Yes |
| Seismic singularity | Monster drop. | 96.7m gp | No | Yes |
| Seismic singularity shard | Monster drop. | 614.7k gp | No | Yes |
| Seismic wand shard | Monster drop. | 1.2m gp | No | Yes |
| Selected iron | Given to you by the Witch at Draynor Manor in exchange for 5 Iron bars. | --- | Yes | Yes |
| Senntisten teleport | Player Made (See Notes). | 6,199 gp | No | Yes |
| Seren | Received from The Archivist in the Hall of Memories after turning in Aagi. | --- | No | Yes |
| Seren godbow | Can be bought from GE or player-made(See notes) | 727.1m gp | No | Yes |
| Seren insignia | The Heart of Gielinor. | --- | No | Yes |
| Seren shard (dark) | Collected in The Light Within quest inside Morvran's library. | --- | Yes | Yes |
| Seren shard (harmony) | Collected in The Light Within quest inside active Crystal Tree. | --- | Yes | Yes |
| Seren shard (integrity) | Collected in The Light Within quest from clues hidden within Baxtorian's journal. | --- | Yes | Yes |
| Seren shard (prudence) | Collected in The Light Within quest inside Lletya's well. | --- | Yes | Yes |
| Seren shard (wisdom) | Collected in The Light Within quest inside the Hefin Cathedral. | --- | Yes | Yes |