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Quest | Members Only |
| Sealed small rune pouch (black) | Player Made (See Notes). | --- | No | Yes |
| Sealed small rune pouch | Player Made (See Notes). | --- | No | Yes |
| Sealed pot | Player made (See Notes Section). | --- | Yes | Yes |
| Sealed message | Given to you by Safalaan, at the Myreque hideout in Meiyerditch. | --- | Yes | Yes |
| Sealed letter | Given to you by Curator Haig Halen at the museum in the eastern part of Varrock. | --- | Yes | Yes |
| Sealed large rune pouch (yellow) | Player Made (See Notes). | 33.4m gp | No | Yes |
| Sealed large rune pouch (red) | Player Made (See Notes). | 33.1m gp | No | Yes |
| Sealed large rune pouch (purple) | Player Made (See Notes). | 32.6m gp | No | Yes |
| Sealed large rune pouch (pink) | Player Made (See Notes). | 32.7m gp | No | Yes |
| Sealed large rune pouch (orange) | Player Made (See Notes). | 32.1m gp | No | Yes |
| Sealed large rune pouch (green) | Player Made (See Notes). | 32.7m gp | No | Yes |
| Sealed large rune pouch (blue) | Player Made (See Notes). | 35.0m gp | No | Yes |
| Sealed large rune pouch (black) | Player Made (See Notes). | 46.3m gp | No | Yes |
| Sealed large rune pouch | Player Made (See Notes) | 67.5m gp | No | Yes |
| Sealed funnel | In your inventory after starting a Flash Powder Factory game. | --- | No | Yes |
| Sealed clue scroll (medium) |
| --- | No | Yes |
| Sealed clue scroll (master) | There is a 1% chance of receiving a Master clue instead of a Elite clue when an Elite clue is found.
Some possible options are:
| --- | No | Yes |
| Sealed clue scroll (hard) |
| --- | No | Yes |
| Sealed clue scroll (elite) |
| --- | No | Yes |
| Sealed clue scroll (easy) |
| --- | No | Yes |
| Seal of the Furies | The Heart of Gielinor; Monster drop. | --- | No | Yes |
| Seal of the Faceless | The Heart of Gielinor; Monster drop. | --- | No | Yes |
| Seal of the Dragon riders | The Heart of Gielinor; Monster drop. | --- | No | Yes |
| Seal of the Cywir | The Heart of Gielinor; Monster drop. | --- | No | Yes |
| Seal of passage | Received from Brundt the Chieftain. | --- | Yes | Yes |
| Seal | Inside Rolo the Stout's chest, upstairs in the Pick and Lute tavern in Taverley. | --- | Yes | No |
| Seahorse follower pet token | This can be won from a Summer loot pinata, hidden within its loot bag. | 9.7m gp | No | No |
| Seahorse balloon | Obtained from inside a Summer pinata loot bag. | 6,397 gp | No | No |
| Seagull wing | Monster drop. | --- | Yes | Yes |
| Sea turtle bait | Player Made (See Notes). | 29.0k gp | No | Yes |
| Sea turtle | Player made (See notes). | 321 gp | No | Yes |
| Sea troll egg decoration | Possible reward from opening Prawn balls. | --- | No | Yes |
| Sea slug glue | Given to you by Bailey, on the Fishing Platform, in exchange for a Dead sea slug. | --- | Yes | Yes |
| Sea slug | Respawn at the Varrock Museum has some sea slugs on display in its Natural History department, which is in the basement. The Apothecary in southern Varrock also seems to have a sea slug pickled in a jar.
Fishing platform. | 0 gp | No | Yes |
| Sea shell | Found randomly on Uncharted Isles. | --- | No | Yes |
| Sea salt | Mined from Salty Crablet on Uncharted Isles and Salty crabletine on Cyclosis; purchased from Yi Yan when in stock. | --- | No | Yes |
| Sea legs potion | Quest item. | --- | Yes | Yes |
| Sea fishing map | Given to you by Swensen the Navigator, south of Rellekka's market, in exchange for the Weather forecast. | --- | Yes | Yes |
| Sea cucumber | Caught in the fishing spot beneath the Wizards' Tower. | --- | No | No |
| Sea chart | Quest item. | --- | Yes | Yes |
| Scythe sharpener | Found inside of the Bookcases. | --- | No | No |
| Sculpting chisel (Zamorak) | Obtained from Copernicus Glyph. | --- | No | Yes |
| Sculpting chisel (Saradomin) | Obtained from Copernicus Glyph. | --- | No | Yes |
| Sculpting chisel (Bandos) | Obtained from Copernicus Glyph. | --- | No | Yes |
| Scrumpled piece of paper | Found in random event when talking to shantay. | 0 gp | No | Yes |
| Scrumpled paper | The Scrumpled paper is obtained randomly by talking to Shantay at the Shantay Pass. It will fall out of his pocket. | --- | No | Yes |
| Scrubbed rock crab carcass | Player made (See Notes Section). | --- | Yes | Yes |
| Scrubbed cockatrice skin | Player made (See Notes Section). | --- | Yes | Yes |
| Scrubbed cave crawler skin | Player made (See Notes Section). | --- | Yes | Yes |
| Scrubbed black unicorn hide | Player made (See Notes Section). | --- | Yes | Yes |
| Scrubbed bear pelt | Player made (See Notes Section). | --- | Yes | Yes |
| Scroll of the dead | Dropped by Skeleton looters (level 60) in the Missing My Mummy quest pyramid. | --- | Yes | Yes |
| Scroll of renewal | Bought from the Rewards trader and Wythien. | --- | No | Yes |
| Scroll of quick teleportation | Bought from the Rewards trader and Wythien. | --- | No | No |
| Scroll of praise | Given to you by Reldo, at the Varrock Castle library, in exchange for an Al kharid flyer. | --- | Yes | Yes |
| Scroll of Daemonheim | Bought from the Rewards trader and Wythien. | --- | No | Yes |
| Scroll of cleansing | Bought from the Rewards trader and Wythien. | --- | No | Yes |
| Scroll fragment 3 | Found after reading Ingram's ramblings. | --- | Yes | No |
| Scroll fragment 2 | Found after reading Ormod's scribblings. | --- | Yes | No |
| Scroll fragment 1 | Found after reading Ingram's notes. | --- | Yes | No |
| Scroll (The Elemental Workshop II) | Obtained by reading the Beaten book. | --- | Yes | Yes |
| Scroll (Royal Trouble) | Given to you by King Vargas, at the castle on Miscellania, | --- | Yes | No |
| Scroll (Making History) | Given to you by Droalak at Port Phasmatys. | --- | Yes | Yes |
| Scroll (Barbarian Assault) | Barbarian Assault, on a table in each of the recruitment rooms. | --- | No | Yes |
| Scrimshaw of vampyrism | Player Made (See Notes). | 873.0k gp | No | Yes |
| Scrimshaw of the elements | Player Made (See Notes). | 515.3k gp | No | Yes |
| Scrimshaw of sacrifice (inactive) | Obtained via Treasure Hunter Promotion. | 4.5m gp | No | Yes |
| Scrimshaw of sacrifice | Treasure Hunter Promotion. | --- | No | Yes |
| Scrimshaw of ranging | Player Made (See Notes). | 682.3k gp | No | Yes |
| Scrimshaw of magic | Player Made (See Notes). | 676.3k gp | No | Yes |
| Scrimshaw of cruelty | Player Made (See Notes). | 581.6k gp | No | Yes |
| Scrimshaw of corruption (inactive) | Obtained via Treasure Hunter Promotion; Obtained from Motherlode Maw; Player Made (See Notes). | 5.0m gp | No | Yes |
| Scrimshaw of corruption | Treasure Hunter Promotion; Player Made (See Notes). | --- | No | Yes |
| Scrimshaw of attack | Player Made (See Notes). | 659.1k gp | No | Yes |
| Scrimshaw of aggression (inactive) | Obtained via Treasure Hunter Promotion. | 1.1m gp | No | Yes |





