Name   |
Location |
Market price |
Quest |
Members Only |
| Supreme overload salve (6) | Player made (See Notes). | --- | No | Yes |
| Supreme ranging potion (1) | Player made (See Notes). | --- | No | Yes |
| Supreme ranging potion (2) | Player made (See Notes). | --- | No | Yes |
| Supreme ranging potion (3) | Player made (See Notes). | --- | No | Yes |
| Supreme ranging potion (4) | Player made (See Notes). | --- | No | Yes |
| Supreme ranging potion (5) | Player made (See Notes). | --- | No | Yes |
| Supreme ranging potion (6) | Player made (See Notes). | --- | No | Yes |
| Supreme reward book | Given to you by Xuan after completing the Supreme jack of trades requirements. | --- | No | Yes |
| Supreme strength potion (1) | Player made (See Notes). | --- | No | Yes |
| Supreme strength potion (2) | Player made (See Notes). | --- | No | Yes |
| Supreme strength potion (3) | Player made (See Notes). | --- | No | Yes |
| Supreme strength potion (4) | Player made (See Notes). | --- | No | Yes |
| Supreme strength potion (5) | Player made (See Notes). | --- | No | Yes |
| Supreme strength potion (6) | Player made (See Notes). | --- | No | Yes |
| Suqah hide | Monster Drop. | --- | Yes | Yes |
| Suqah leather | Made by paying Rimae Sirsalis 100 coins to tan your Suqah hide. | --- | No | Yes |
| Suqah tooth | Monster drop; Traded from Skulgrimen (See Notes). | --- | Yes | Yes |
| Surfboard emote token | Obtained by skilling on the beach, killing Clawdia, or purchased from Flo for 33 Runecoins. | --- | No | No |
| Surfboard shield token | A Surfboard shield token is an item that can be won from a summer piñata loot bag, received upon destroying a summer loot piñata. | 0 gp | No | Yes |
| Surok's letter | Given to you by Surok Magis, at the Varrock Library. | --- | Yes | Yes |
| Survey | Given to you by Freda, at her house west of Burthorpe, in exchange for Spiked boots. | --- | No | No |
| Survivalist's potion | Player made (See Notes Section). | 0 gp | No | Yes |
| Survivor's journal | Found West of the shipwreck on the beach of Anachronia. | --- | No | Yes |
| Suspect sketch | Obtained during the While Guthix Sleeps quest. | --- | Yes | Yes |
| Suspicious note | Received from Doric. | --- | No | No |
| Sven's last map | Received from Olaf Hradson after giving Ingrid Hradson a crude carving, giving Volf Olafson a cruder carving, giving food to Olaf, and relighting his fire with damp planks. | --- | Yes | Yes |
| Swag bag | Once a reward from the discontinued Squeal of Fortune; Randomly obtained from opening large parcels (May 2018). | --- | No | Yes |
| Swagger stick | Once a reward from the discontinued Squeal of Fortune; Randomly obtained from opening large parcels (May 2018). | --- | No | Yes |
| Swamp lizard quota ticket | Bought at the reward shop of the Big Chinchompa Distraction and Diversion for 10 points. | --- | No | Yes |
| Swanky boots | Reward from the Gunnar's Ground quest. | --- | Yes | No |
| Sweetgrub | By using raw rat meet on a sweetgrub mound. | 0 gp | No | Yes |
| Sweets | Trick children near lumbridge who are trick or treating.
| --- | No | No |
| Swift gloves | Claimed from the Strange Face in the Dominion Tower lobby after killing 500 bosses. | --- | No | Yes |
| Sword blueprints | No longer found within game, though they still exist if found or won in 2013. | --- | No | No |
| Sword fragment | Player made (See Notes Section). | --- | Yes | Yes |
| Sword of Edicts engram | Found at the base of the Sword of Edicts in the Wilderness, near the Divination wisps (See Notes for location image). | --- | No | Yes |
| Sword of Edicts engram (charged) | Player Made (See Notes). | --- | No | Yes |
| Sword Polishing Kit | Purchased from Egil's Artisans' Workshop rewards shop. | --- | No | Yes |
| Sword pommel | Search the tomb dolmen in Bervirius's tomb on Cairn Isle. | --- | Yes | Yes |
| Swordfish (Raktuber) | Located on a hat-rack, on the penguin submarine. | --- | Yes | Yes |
| Swordfish gloves | Purchased from the Fist of Guthix lobby. | --- | No | No |
| Symptoms list | Given to you by Fairy Nuff, at her house north of Zanaris' bank. | --- | Yes | Yes |
| Saradomin dragonhide blessed set | Player Made (See Notes). | Unknown | No | Yes |
| Saragorgak star crown | Unknown | --- | No | Yes |
| Scroll fragment 1 | Found after reading Ingram's notes. | --- | Yes | No |
| Scroll fragment 2 | Found after reading Ormod's scribblings. | --- | Yes | No |
| Scroll fragment 3 | Found after reading Ingram's ramblings. | --- | Yes | No |
| Scythe key | Found in the last statue room, before the room with the shrine of the son. | --- | Yes | No |
| She-wolf trophy | Unknown | --- | No | Yes |
| Silver Dominion medal | Unknown | --- | No | Yes |
| Silver hawk | Possible reward from Treasure Hunter minigame during the promotional period from 13th to 16th of March 2015; Purchased from Rare token store. | --- | No | No |
| Singing bowl | Unknown | --- | No | Yes |
| Skull key | Found in the shrine in one of the safe rooms of the mansion. | --- | Yes | No |
| Snake key | Found on the key hooks near the ladder in the basement of the mansion. | --- | Yes | No |
| Snorkel token | Obtained by skilling on the beach, killing Clawdia, or purchased from Sheldon for 20 Runecoins. | --- | No | No |
| Songbird recorder | Unknown | --- | No | Yes |
| Spear of Annihilation | Unknown | --- | No | Yes |
| Spear of Annihilation tip | Unknown | --- | No | Yes |
| Spear of Annihilation with shaft | Unknown | --- | No | Yes |
| Spear of Annihilation with shaft + spokes | Unknown | --- | No | Yes |
| Spherical astrolabe | Unknown | --- | No | Yes |
| Spiked dog collar | Unknown | --- | No | Yes |
| Springy pet token | Can be bought from the Rare token store for 7,000 tokens. | --- | No | No |
| Statue key | Found on the faceless servant after you talk to them. | --- | Yes | No |
| Stormguard gerege | Unknown | --- | No | Yes |
| Sunglasses | Possible reward from Treasure Hunter minigame during the promotional period from 13th to 16th of March 2015; Purchased from Rare token store. | --- | No | Yes |
