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Name   |
Location |
Market price |
Quest | Members Only |
| Silver Dominion medal | Unknown, please submit. | --- | No | Yes |
| Sign of item protection | Player made (See Notes Section). | 3,704 gp | No | Yes |
| Shoulder bone | Dropped by any giants only during the Fur 'n' Seek quest. | --- | Yes | Yes |
| Shimmering honeycomb | Player Made (See Notes). | 397.2k gp | No | Yes |
| Shield of Arrav (Dimension of Disaster) | Obtained by combining both broken halves of the shield together during the quest Dimension of Disaster. | --- | No | Yes |
| Shield left half (dragon square) | Monster drop. | 69.9k gp | Yes | Yes |
| Shengo potion (unf) | Player made (See Notes Section). | --- | No | Yes |
| Sheep bones (1-4) | Dropped by diseased sheep. | --- | Yes | Yes |
| Shark jawbone | Possible reward from opening a Prawn ball. | 1,029 gp | No | Yes |
| Shard of malice weapon token | Dropped by the Giant Mimic. | 0 gp | No | Yes |
| Shard of havoc weapon token | Dropped by the Giant Mimic. | --- | No | Yes |
| Shard of energy weapon token | Dropped by the Giant Mimic. | --- | No | Yes |
| Shaman's poncho | This item is obtained from the Treasure Hunter minigame.
Available as a rare reward from Familiarisation D&D. | --- | No | Yes |
| Shaman's headdress add-on | Won from Treasure Hunter or Familiarisation | --- | No | Yes |
| Shaikahan bones | Dropped by Karamja jungle monster (Shaikahan). | 65.5k gp | No | Yes |
| Shadow diamond | Dropped by Damis in his lair, west of the Fishing Guild. | --- | Yes | Yes |
| Seren shard (harmony) | Collected in The Light Within quest inside active Crystal Tree. | --- | Yes | Yes |
| Selected iron | Given to you by the Witch at Draynor Manor in exchange for 5 Iron bars. | --- | Yes | Yes |
| Seeping elm longbow (u) | Player made (See Notes Section). | 0 gp | No | Yes |
| Seeping elm longbow | Player made (See Note Section) or Monster drop. | 0 gp | No | No |
| Seeker's charm (Dungeoneering) | Monster Drop. | 0 gp | No | Yes |
| Seed bag (Extinction) | Received from the Plantkeeper on Iaia. | --- | Yes | Yes |
| See-no-evil monkey hat | Possible reward from the discontinued Squeal of Fortune, during Mad May; Possible reward from Treasure Hunter, during Smashing Relics promotion. | --- | No | Yes |
| Second-Age sword | Possible reward from a Reward casket (master). | 215.0m gp | No | Yes |
| Second-Age staff | Possible reward from a Reward casket (master). | 236.9m gp | No | Yes |
| Second-Age robe top | Possible reward from a Reward casket (master). | 702.4m gp | No | Yes |
| Second-Age robe bottom | Possible reward from a Reward casket (master). | 719.4m gp | No | Yes |
| Second-Age range top | Possible reward from a Reward casket (master). | 254.5m gp | No | Yes |
| Second-Age range legs | Possible reward from a Reward casket (master). | 270.9m gp | No | Yes |
| Second-Age range coif | Possible reward from a Reward casket (master). | 89.7m gp | No | Yes |
| Second-Age platelegs | Possible reward from a Reward casket (master). | 793.6m gp | No | Yes |
| Second-Age platebody | Possible reward from a Reward casket (master). | 534.5m gp | No | Yes |
| Second-Age mage mask | Possible reward from a Reward casket (master). | 176.8m gp | No | Yes |
| Second-Age full helm | Possible reward from a Reward casket (master). | 153.8m gp | No | Yes |
| Second-Age bow | Possible reward from a Reward casket (master). | 243.5m gp | No | Yes |
| Second wind scroll (tier 9) | Player made (See Notes Section). | 0 gp | No | Yes |
| Second wind scroll (tier 8) | Player made (See Notes Section). | 0 gp | No | Yes |
| Second wind scroll (tier 7) | Player made (See Notes Section). | 0 gp | No | Yes |
| Second wind scroll (tier 6) | Player made (See Notes Section). | 0 gp | No | Yes |
| Second wind scroll (tier 5) | Player made (See Notes Section). | 0 gp | No | Yes |
| Second wind scroll (tier 4) | Player made (See Notes Section). | 0 gp | No | Yes |
| Second wind scroll (tier 3) | Player made (See Notes Section). | 0 gp | No | Yes |
| Second wind scroll (tier 2) | Player made (See Notes Section). | 0 gp | No | Yes |
| Second wind scroll (tier 10) | Player made (See Notes Section). | 0 gp | No | Yes |
| Second wind scroll (tier 1) | Player made (See Notes Section). | 0 gp | No | Yes |
| Second stone fragment | The second stone fragment is found South East of the Ancient statue on Mazcab. | --- | No | Yes |
| Second dragonkin journal | Obtained from killing the Queen Black Dragon and claiming the reward from the chest. | --- | No | Yes |
| Seasoned chompy | Player made (See Notes Section). | --- | Yes | Yes |
| Searing overload potion (6) | Player made (See Notes). | --- | No | Yes |
| Searing overload potion (5) | Player made (See Notes). | --- | No | Yes |
| Searing overload potion (4) | Player made (See Notes). | --- | No | Yes |
| Searing overload potion (3) | Player made (See Notes). | --- | No | Yes |
| Searing overload potion (2) | Player made (See Notes). | --- | No | Yes |
| Searing overload potion (1) | Player made (See Notes). | --- | No | Yes |
| Seal of the Dragon riders | The Heart of Gielinor; Monster drop. | --- | No | Yes |
| Seahorse balloon | Obtained from inside a Summer pinata loot bag. | 5,246 gp | No | No |
| Sea troll egg decoration | Possible reward from opening Prawn balls. | --- | No | Yes |
| Sea legs potion | Quest item. | --- | Yes | Yes |
| Scroll of quick teleportation | Bought from the Rewards trader and Wythien. | --- | No | No |
| Scroll of Daemonheim | Bought from the Rewards trader and Wythien. | --- | No | Yes |
| Scrimshaw of corruption (inactive) | Obtained via Treasure Hunter Promotion; Obtained from Motherlode Maw; Player Made (See Notes). | 4.9m gp | No | Yes |
| Scrimshaw of corruption | Treasure Hunter Promotion; Player Made (See Notes). | --- | No | Yes |
| Scrimshaw of aggression (inactive) | Obtained via Treasure Hunter Promotion. | 955.9k gp | No | Yes |
| Scrimshaw of aggression | Treasure Hunter Promotion. | --- | No | Yes |
| Scorpion meat | Possible reward from the Rewards box in the lobby of the Dominion Tower. | --- | No | Yes |
| Scorpion cage | Given to you by Thormac. | --- | Yes | Yes |
| Schematic (Dondakan) | Given to you by Dondakan the Dwarf in Keldagrim. | --- | Yes | Yes |
| Scentless potion flask (6) | Player made (See notes section). | --- | No | Yes |
| Scentless potion (3) | Player made (See Notes Section). | --- | No | Yes |
| Scentless potion (2) | Result from drinking a scentless potion (3). | 0 gp | No | Yes |
| Scentless potion (1) | Result from drinking a scentless potion (2). | --- | No | Yes |
| Sassafras Weaving Ribbon | Player made (See Notes Section). | --- | Yes | Yes |
| Saradominist soulstone | Monster drop. Commander Zilyana hard mode only. | --- | No | Yes |
| Saradominist ceremonial robe top | This item can be purchased for 500 Astromancer credits. | 0 gp | No | No |
| Saradominist ceremonial robe bottom | Can be purchased for 250 Astromancer credits. | --- | No | No |
